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First ONC-certified FHIR® API in 2016

Healthcare interoperability, built on proven infrastructure.Powering the next era of clinical AI.

Built in-house from the ground up, Carefluence’s ONC-certified FHIR® R4 platform connects healthcare systems and enables secure, governed, real-time clinical data access for applications and AI agents.

The Carefluence® Platform

Connecting healthcare systems.Through one certified FHIR® infrastructure.

From EHRs and HIEs to medical devices and legacy systems, Carefluence brings healthcare interoperability together through one in-house-developed FHIR® R4 platform, with governed access for applications and AI agents.

Who We Serve

Built for the complexityof healthcare interoperability.

From health systems and EHR vendors to payers, MedTech and healthcare AI companies, Carefluence provides certified interoperability infrastructure for connecting healthcare systems, applications and clinical data.

One Platform

One platform for all of it.Connect. Normalize. Secure. Enable AI.

Retire the point-to-point interfaces. Run EHR connections, HIE feeds, lab and device data, HL7® v2 and X12 messages, SMART apps, partner APIs, patient access and AI agents on one certified FHIR® platform.

Connect

Every system gets one FHIR® front door

Connect EHRs, HIEs, applications, medical devices, and legacy systems through a unified FHIR® platform.

FHIRone™ and adapters
HL7® v2 feedADT^A04 · MLLPAcknowledged
fhir/r4PatientLiveEncounterLiveObservationLiveConditionLive
Normalize

One data model, whatever the source

Transform fragmented healthcare data into consistent, standards-based FHIR® resources ready for exchange, analytics, and AI.

Data Translator
SourcesCarefluence®Output
HL7® v2C-CDAX12Direct
Data Translator
FHIR® R4
Secure

Access governed for every user, app and agent

Govern access for users, applications, models, and AI agents with standards-based identity, authentication, and authorization.

OAuth & OpenID
scheduling-appOAuth 2.0 · SMART
patient/Patient.readGrantedpatient/Appointment.writeGranteduser/Observation.readGrantedsystem/*.writeDenied
Enable AI

Real-time clinical context for AI

Provide applications and intelligent agents with secure, governed, real-time access to connected clinical data.

Carefluence MCP server
Agent activityMCP
  1. tool: search_patients · 1 match
  2. tool: get_conditions · 4 resources
  3. tool: get_medications · 7 resources
  4. scope check: Coverage.write · blocked
  5. summary returned for clinician review
Platform Scale

Massive throughput across healthcare ecosystems.Developed in-house; not an open-source wrapper.

Carefluence is mission-critical infrastructure operating at global scale. Managing hundreds of thousands of patient records and millions of interactions, it bridges disparate healthcare systems with a 100% integration success rate.

Patient interactions~11.63M

Discrete health engagements, 2022–2025.

Enterprise partners143+

Telemedicine, dialysis, EHRs.

Go-live success rate100%

Industry average: 80–90%.

ONC-certified since2016

The first ONC-certified FHIR® API, recertified in 2022.

Years offering FHIR®13+

Offering interoperability solutions since the Argonaut Project in 2013.

Introducing Carefluence AI

Reimagine healthcare operations with Carefluence AI.

Intelligent healthcare agents that automate workflows, unlock data, and help your teams work faster while maintaining full control, transparency, and compliance.

Outcome

Less manual authorization work

Automates eligibility checks, data gathering, and authorization workflows, with a person approving every submission.

Carefluence AIConnected · FHIR® R4
  1. Request received
  2. Response generated

Start the prior auth for M. Chen's lumbar spine MRI.

patient/Coverage.read · patient/ServiceRequest.readNothing is sent to a payer without your approval.
Illustrative conversation
Carefluence MCP

Forward-Looking Use Cases

See how Carefluence MCP transforms clinical workflows.

Explore all possibilities

Generative Clinical Decision Support

AI agents that can instantly summarize complex patient context and support clinicians with evidence-informed insights at the point of care.

Automated Documentation

Auto-generate accurate SOAP notes, discharge summaries, and care plans by feeding the AI the full clinical encounter context.

Intelligent Telemedicine Assistants

Context-aware AI chatbots that improve virtual visits by having access to real-time medical history during the conversation.

AI-Driven Population Health

Perform predictive analytics for risk scoring and community-wide insights using standardized data across your population.

See Carefluence in action

We solve interoperability today.The same infrastructure powers AI tomorrow.

The ONC-certified FHIR® platform that connects your EHRs, HIEs, devices and legacy systems now is the same foundation that gives your applications and AI agents governed, real-time clinical data next. License it, or have Carefluence build with you.